‘Be careful. You could get HIV, you could get HIV!’ This is the voice Greg used to hear every time he had sex. That was until he started taking a pill aimed at preventing him getting infected.

Greg was a participant in the PROUD study into the effectiveness of the drug Truvada (emtricitabine and tenofovir disoproxil fumarate) as pre-exposure prophylaxis (PrEP) for men who have sex with men.1 PROUD, which took place in English cities, found an 86-per-cent reduction in the risk of HIV infection for those taking Truvada, compared with a control group which did not.